Cosmic Peptides research library

DMSO

A polar aprotic solvent that dissolves nearly every peptide, used for concentrated stocks that are then diluted into aqueous buffer.

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Dimethyl sulfoxide dissolves hydrophobic peptides that no aqueous solvent will take. A stock in DMSO is diluted into buffer so that the final DMSO is at or below 0.1–1% by volume, since above that it affects proteins and cells in assays.

DMSO slowly oxidizes free cysteine and methionine, is hygroscopic, and is viscous enough to pipette badly; a peptide with a free thiol should not be stored in it.

See also

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Text

Cosmic Peptides. (2026, October 30). DMSO: glossary entry. Cosmic Peptides Research Library. Retrieved October 30, 2026, from https://cosmicpeptides.com/research/glossary/dmso

BibTeX

@misc{cosmicpeptides_research_glossary_dmso,
  author       = {{Cosmic Peptides}},
  title        = {DMSO: glossary entry},
  howpublished = {Cosmic Peptides Research Library},
  year         = {2026},
  month        = oct,
  url          = {https://cosmicpeptides.com/research/glossary/dmso},
  urldate      = {2026-10-30},
  note         = {Last reviewed 2026-10-30}
}

RIS

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AU  - Cosmic Peptides
TI  - DMSO: glossary entry
T2  - Cosmic Peptides Research Library
PB  - Cosmic Peptides
PY  - 2026
DA  - 2026/10/30
UR  - https://cosmicpeptides.com/research/glossary/dmso
Y2  - 2026/10/30
LA  - en
ER  -

Cite the date the page was last reviewed, October 30, 2026, as its version. Reference managers such as Zotero can save this page directly.

For in vitro laboratory research only. Not for human or veterinary use. This library describes chemistry, analytical methods and published laboratory research; it gives no guidance on use in people or animals.